The evolution of allergen and non-specific immunotherapy: past achievements, current applications and future outlook
نویسندگان
چکیده
منابع مشابه
Allergen Immunotherapy: Past, Present, and Future.
Allergen-specific immunotherapy (AIT), although in clinical use for more than a century, is still the only causal treatment of allergic diseases. The safety and efficacy of AIT has been demonstrated in a large number of clinical trials. In addition to allergy symptom reduction AIT plays an essential role in preventing new allergies and asthma and shows long-term effects after discontinuation of...
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متن کاملMechanism of Regulatory T Cells During Allergen-Specific Immunotherapy: from the Past to Future
Since the first trial reported by Noon about a century ago [1], allergen-specific immunotherapy (SIT) by repeated subcutaneous administration of increased doses of allergen extracts has a long-lasting effect on immunologic tolerance to common environmental allergens [2-4]. Allergen-specific subcutaneous immunotherapy (SCIT) has been effectively used for the treatment choice for allergic rhiniti...
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The role of allergen-specific immunotherapy in asthma (AIT) is still a matter of debate. Actually, many controlled clinical trials have proved efficacy and safety of AIT in asthma, and some published meta-analyses, despite some methodological weaknesses, have confirmed these findings, the most recent and convincing being a meta-analysis on injection AIT studies. For sublingual AIT evidences do ...
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ژورنال
عنوان ژورنال: Expert Review of Clinical Immunology
سال: 2014
ISSN: 1744-666X,1744-8409
DOI: 10.1586/1744666x.2015.977260